The first London derby of the 2026/27 Premier League season takes centre stage at the Emirates, where defending champions Arsenal welcome Chelsea in an early test of their title credentials.
Mikel Arteta’s side have made a strong start, keeping clean sheets in both matches. They beat Coventry 3-0 before securing a hard-fought 1-0 win away to Aston Villa. Their defensive organisation and control in possession have been particularly impressive.
Chelsea, meanwhile, have shown plenty of attacking flair under new boss Xabi Alonso. Their 4-3 win over Brighton highlighted their attacking approach, although defensive lapses remain a concern.
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Recent history favours Arsenal, who are unbeaten in their last 11 meetings with Chelsea in all competitions, including a 2-1 league win at the Emirates in March.
The contest between Arsenal’s centre-backs and in-form forward João Pedro could prove decisive, while Bukayo Saka’s ability to exploit space out wide could give the hosts another advantage.
Prediction: Arsenal 2-3 Chelsea
Everton vs Manchester United
[Hill Dickinson Stadium, Sunday, 4pm]
Everton host Manchester United in an intriguing contest between two sides with contrasting starts to the season.
The Toffees are unbeaten after a 2-0 home win over Crystal Palace and a resilient 1-1 draw at Bournemouth. They have conceded just once and will look to use their compact shape and pressing to disrupt United’s build-up.
United arrive with renewed confidence after a 5-2 win over Ipswich Town, which helped erase the disappointment of their 2-0 opening-day defeat by Hull City.
Bruno Fernandes has been influential in midfield, but defensive lapses remain a concern. United have won six of their last eight league meetings with Everton, although this trip is unlikely to be straightforward.
Everton’s organisation and home support should make this a competitive encounter.
Prediction: Everton 1-1 Manchester United
Inter Milan vs Napoli
[San Siro, Saturday, 7pm]
The standout Serie A fixture of the weekend sees Inter Milan host Napoli at the San Siro in a clash with early title implications.
The reigning champions have made an impressive start under Cristian Chivu, beating Monza 4-1 before edging Cagliari 1-0. Inter have looked sharp, confident and dangerous in attack.
Napoli, under Massimiliano Allegri, began with a 2-0 win at Genoa but then suffered a surprise 2-1 home defeat by Como. Defensive concerns have been compounded by a growing injury list.
Recent meetings between the sides have produced plenty of drama, including a 2-2 draw at the San Siro in January after Napoli won 3-1 earlier in 2025.
Another open contest is expected, but Inter’s greater squad depth and home advantage could prove decisive.
Prediction: Inter Milan 3-1 Napoli
