Two British people are self-isolating at home in the UK after potential exposure to hantavirus on a cruise ship struck by the outbreak, the UK Health Security Agency (UKHSA) has said.
They left MV Hondius at St Helena in late April, flying back to the UK via Johannesburg. Neither had symptoms but contacted health officials when they heard of the ship's cases.
A 56-year-old British man is in a stable condition after being evacuated from the ship on Wednesday. He has been named as former police officer Martin Anstee by media outlets.
Three people have died on the ship, which set sail from Argentina a month ago, following the hantavirus outbreak.
The British man was among three people evacuated from the ship on Wednesday to the Netherlands for treatment, operator Oceanwide Expeditions said.
Prof Robin May, chief scientific officer at the UKHSA, told BBC Breakfast it was his understanding that "he is doing well".
"He is going to be under investigation for some time. I'm very pleased he's now in hospital and receiving the treatment he needs," May said.
Anstee's wife, Nicola, told the Daily Telegraph it had been "a very dramatic few days".
"He's relieved to be off the ship. He had it quite mild then it got a bit more serious and now he's stable again.
"The fear with this virus is it can deteriorate very quickly so it's been a bit up and down for him. I don't believe he's in imminent danger now but it was horrible."
The other evacuees were Dutch and German. Oceanwide Expeditions said the German evacuee was "closely associated" with a German woman who died on board the ship on 2 May.
Hantavirus typically spreads from rodents, but health experts believe that in this case, it may have passed between humans that were in close contact.
The Andes strain of the virus has been confirmed in two of the ship's passengers, according to South Africa's health minister, and experts have observed the strain spreading between human patients in previous outbreaks, although very rarely.
It can take between one and eight weeks for symptoms to appear. May told BBC Radio 4's Today programme that "general expert consensus is now consolidating around six weeks" for the incubation period.
Following the outbreak, the UKHSA said the risk to the UK population was "very low" and there was "no need for concern among the general public".
About 150 people are still aboard the cruise ship under "strict precautionary measures", Oceanwide Expeditions has said.
They include 19 passengers and four crew members listed as British, according to figures released by the operator on Tuesday.
Spanish authorities have given permission for the ship to dock in the Canary Islands, despite concerns from local officials.
The US Department of State said it is in "direct contact" with affected passengers and the risk to the American public is "extremely low" at this time, according to the Centers for Disease Control and Prevention (CDC).
Eight people, including a Swiss citizen, are suspected to have contracted the virus, said the World Health Organization (WHO).
The UKHSA said the Britons on the ship would be flown home on a charter flight, probably from the Canary Islands as long as they did not have symptoms.
They would then have to self-isolate or be put into quarantine potentially for up to six weeks, depending on the timing of their last potential exposure to the virus.
May told BBC Radio 4's Today programme that they would probably be asked to self-isolate at home, but that "depends on individual circumstances".
He said his officials would be getting in touch with the contacts of anyone who may have been exposed to the virus including family members, anyone who shared rooms on the ship with them or anyone who sat next to them on a long haul flight.
The contact tracing work has been "quite a mammoth effort", he told BBC Breakfast, and one "we will continue to do... for some time".
The World Health Organization (WHO) said the risk to the wider public was low and the virus rarely spreads through human to human transmission and only after close contact.
It is still unknown where the outbreak originated from and if people other than cruise ship passengers have been infected with the disease.
One passenger who disembarked earlier in the cruise said the ship's staff initially assumed the illness was not infectious.
Travel blogger Ruhi Cenet told the BBC: "I was very unhappy because they did not take the right precautions for the first couple of weeks.
"They didn't know as well, I cannot fully blame them, but they should at least have thought of the possibility of the contagious disease."
He shared a video with the BBC taken on 12 April, showing the ship's captain telling passengers that a man had passed away due to "natural causes".
In the video, the captain told passengers a doctor had said the individual was "not infectious".
Oceanwide Expeditions told the BBC the first report of hantavirus came "after disembarkation at St Helena" - over a week after the video was taken.
The operator said it "acted as we reported via our press updates" following the first identified hantavirus case on 4 May.
The three people with symptoms - who also include a 41-year-old Dutch crew member and 65-year-old German - were evacuated from the vessel to receive medical help in the Netherlands, the WHO said.
The Foreign Office has said it was "working urgently" to get British nationals stuck on board the MV Hondius home safely.
Foreign Secretary Yvette Cooper said the situation was "very serious and deeply stressful for those affected and their families".
The Foreign Office said the UK response to the outbreak was being led by the UKHSA working with the WHO.
Consular staff are in contact with British nationals onboard the ship and the Foreign Office has been "working with other countries to facilitate the medical evacuations, to support our Overseas Territories and to get British nationals home safely as quickly as possible", Cooper added.
The UKHSA is also working with governments in St Helena, Tristan de Cunha and Ascension Island on isolation, contact-tracing efforts and response protocols.
The vessel will sail to the Canary Islands where all passengers will be evacuated at the Granadilla port in Tenerife, Spain's health minister Monica Garcia said on Wednesday.
Spanish passengers will be quarantined in Madrid, while those from other countries will be repatriated if they have no symptoms, Garcia said.
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